With respect to the action of Basti in general, it is important to know the procedure and the pathway that it covers. Basically Basti or enema is given through the anal route and is pushed into the large intestine with a controlled uniform force. The medicine thus moves from the anus to the large intestine upto the ileocaecal junction. The content and composition of the medication being honey, salt, oil, paste (Herbal or herboanimal) and decoction where the main medicum is the decoction which is in high proportion will lead to considerable irritation of the walls initiating secretions and clearing the walls of the intestine. With the presence of Honey and oil the harmful effect of the decoction namely dryness and possible inflammation due to irritation is lessened. Honey and salt are considered to be good in catalysing the process of absorption which will lead to the absorption of the important components of Kashayam, taila and the paste into the body thus aiding in the supply of medication, nourishment to fight against the disease through intestinal routes. For enhancement of the benefit, if the oils are processed with different medicinal herbs such that it also gives a local healing effect too, then it will be an added benefit. 

Not only this, it is also accepted that there is considerable absorption of water, salt, protein, carbohydrates and fat from the large intestine which makes the media all the more useful for giving adequate nourishment along with local repairing of the intestines. The absorption is more when the pH of the contents is basic while it is less when it is acidic. Large intestines are a preferred site for the absorption of proteins as the hydrolysis of these is prevented giving a better chance of providing nutrition to the body. But the absorption is largely dependent on the medicaments that is being used in the process where the role of Asthapanopaga substances is seen. Now these absorbed nutrients and potential properties of the medicinal substances that are processed in the decoction, will reach the heart through the portal and iliac veins that drain to Inferior Venacava as these two are the main vessels that are involved in the venous drainage of the large intestine, anus and rectum. Thus the nutrients and properties of medicaments reach all parts of the body. Moreover, ENS (Enteric Nervous System) which is referred as the second Brain of the body is also stimulated by the potentiated properties and nutrients that get absorbed during the procedure. The total minimum duration of retention being 45 minutes, the evacuation is to happen after or later which if doesn’t then will lead to different harmful effects unlike Anuvasana Basti. This is because, the water being the main medium of the material, the absorption will be maximum in this method where the larger the time it stays, more will be its effect. Hence, to avoid further irritation and secretion leading to inflammation, it is always said to be evacuated forcibly if it doesn’t come out by itself. 

Here the substances or circumstances that are classified as asthapanopaga will either enhance the level of nutrients as in case of foods, potential properties as in case of medicine or the reduction of the time duration to accomplish the benefits by different advised lifestyle. Thus, leading to the increased benefits of the procedure for which it is undertaken. Basically, the procedure is the one that performs biopurification of intestines and also helps in transmitting the vital medicinal substances that are helpful in the control and cure of many diseases. Hence the combination of the substances form a important part of the process for it to give the maximum benefits.