The most common correlation given to the Action is Laxatives. The main purpose of these class of drugs is to relieve constipation and is commonly employed to address the condition. But these group of drugs are classified into various types namely Bulk promoting laxatives, Osmotic laxatives, Prokinetic agents, Lubricating agents, Stimulant laxatives, Surface active agents, etc (REF: Bashir A, Shadrav A, Sizar O. Laxatives. [Updated 2020 Apr 23]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK537246/)
Laxatives are defined as that class of substances that loosen stools and increase bowel movements.
The Bulk laxatives are those which have fibers or hydrophilic contents that absorb water and increase their bulk and inturn increase the bulk of stools. They also help in retaining the water content of the stools making it more easier for evacuation.
The Osmotic laxatives on the other hand are those which draw water into the stools by altering the osmotic pressures and lowering the intestinal pH. Even it can stimulate peristaltic movements too. This is described in the context of ANULOMANA.
The prokinetic agents work on intrinsic neurons releasing acetylcholine and inducing mucosal secretion (Bashir A, Shadrav A, Sizar O. Laxatives. [Updated 2020 Apr 23]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK537246/)
The lubricating agents are those which lubricate the lumen of the intestine facilitating the easy evacuation of stools.
The Stimulant laxatives works by stimulating the colon mucosa such that the water and electrolytes are secreted from the mucosal wall into the stools resulting in the increase of bulk along with contributing to perstalistic movements.
The Surface active agents lower the surface tension of the stools leading to absorption of water and fat into them leading to softening and increase in bulk of the stool.
Other than these there are medicines which act in different mechanism but ultimately result in the increase of water in the stools or other ways for easy evacuation of the stools relieving constipation.